We are currently aware of an issue with MacOS Big Sur where Geneious may crash after you restart your computer. Please see this article for more information about this issue.
Note that when opening Geneious Prime for the first time on an M1 mac users may receive the message "Geneious Prime.app can't be opened because Apple cannot check it for malicious software". We are still investigating the cause of this. As a workaround, you can run Geneious by going to Applications, right-clicking on the Geneious Prime icon and choosing Open.
Geneious Prime is not optimized for the M1 architecture so performance gains from the new chips may be limited. Geneious Prime requires x86 Java (which it is bundled with) and cannot run with the native ARM64 Java.
Further information on running Geneious Prime on the MacOS Big Sur operating system is available at this link.